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Wednesday, July 29, 2020 | History

4 edition of In vitro study of bone marrow derived progenitor cells in liver-like microenvironments found in the catalog.

In vitro study of bone marrow derived progenitor cells in liver-like microenvironments

Alireza Khademhosseini

In vitro study of bone marrow derived progenitor cells in liver-like microenvironments

by Alireza Khademhosseini

  • 17 Want to read
  • 36 Currently reading

Published by National Library of Canada in Ottawa .
Written in English


Edition Notes

Thesis (M.A.Sc.) -- University of Toronto, 2001.

SeriesCanadian theses = -- Thèses canadiennes
The Physical Object
FormatMicroform
Pagination2 microfiches : negative.
ID Numbers
Open LibraryOL20884715M
ISBN 100612629163
OCLC/WorldCa52374510


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In vitro study of bone marrow derived progenitor cells in liver-like microenvironments by Alireza Khademhosseini Download PDF EPUB FB2

Thus, hESC-derived hepatic progenitor cells after the DE stage can be used as an alternative to bioptent liver progenitor/stem cells, In the present study, we treated the hESC-derived hepatic.

Hepatocytes Derived From Adult Stem Cells. In vitro, MSC from human bone marrow and adipose tissue differentiated to hepatocyte-like cells closely related to. Hence, it is accurate to say that as a result of hepatocytes, the shortage of human liver donors is the limiting factor in the development of this therapeutic approach.

Other sources such as hematopoietic stem cells, bone marrow–derived mesenchymal stem cells, and fetal liver progenitors, have also been : Pilar Sainz-Arnal, Iris Pla-Palacín, Natalia Sánchez-Romero, Manuel Almeida, Sara Morini, Estela Sol. The liver is a very complex organ that ensures numerous functions; it is thus susceptible to multiple types of damage and dysfunction.

Sinceorthotopic liver transplantation (OLT) has been considered the only medical solution available to patients when most of their liver function is lost. Unfortunately, the number of patients waiting for OLT is worryingly increasing, and Author: Antonietta Messina, Eléanor Luce, Marwa Hussein, Anne Dubart-Kupperschmitt.

In an extreme case, it is possible to reaggregate suspended bone marrow cells, including so many blood cells, into bone marrow-like tissue. As explained in Section 3, materials that do not have biological adhesiveness (e.g., hydrogel beads) can contribute to the formation of aggregated state together with other cells [4].Author: Nobuhiko Kojima, Fumiya Tao, Hirotaka Mihara, Shigehisa Aoki.

P T he therapeutic effect of human bone marrow-derived clonal mesenchymal stem cells in a rat spinal cord injury model Jin IG, Lim SS, Hwang SJ* Seoul Nat’l Univ., Korea Kim MH, Kim KH, Park SR, Yoon SH, Song SU, Choi BH* Inha Univ., Korea P A denoviral mediated interleukin(ad:rat iL) gene transfer in rat skin allograft.

The mechanotransduction is the process by which cells sense mechanical stimuli such as elasticity, viscosity, and nanotopography of extracellular matrix and translate them into biochemical signals.

The mechanotransduction regulates several aspects of the cell behavior, including migration, proliferation, and differentiation in a time-dependent manner.

Several Cited by: 1. In vitro culture of hepatocytes (liver cells) is a challenging culture system. Despite a volume of research, the effective biomaterials for hepatocyte culture that sustain a high level of biological function over an extended culture period and induce 3-dimensional (3-D) liver-like tissue structure remain elusive.

In this article, a summary of the currently available polymeric biomaterials for. GLOBAL ASSESSMENT OF STEM CELL ENGINEERING. for example in bone marrow transplantation.

Stem cells can also now be artificially grown. Stem Cells in Regenerative Medicine - Free download as PDF File .pdf), Text File .txt) or read online for free. stem cells. Multipotency Ability to form multiple cell lineages which form an entire tissue, usually specific to one germ layer, e.g.

adult stem cells. Oligopotency Ability to form two or more cell lineages in a tissue, e.g. neuronal stem cells with ability to form different neurone types. Mouse bone marrow-derived cells were cultured as unstimulated M0 macrophages or were stimulated into an M1 phenotype using lipopolysaccharide and interferon-γ or into an M2 phenotype using interleukin The macrophage phenotypes were verified using flow cytometry for surface marker analysis and cytokine bead array for cytokine profile assessment.

The former issue is one of the plasticity of the bone marrow stem cells, and the latter may be more an issue of the plasticity of the bone marrow-derived cell lineages.

If a bone marrow stem cell can ever be instructed to be a gastrointestinal stem cell, it should be capable of undertaking all the functional duties of a gastrointestinal stem. In vivo, cells in different tissues are exposed to a wide range of oxygen concentrations, and yet in vitro models almost exclusively expose cultured cells to higher, atmospheric oxygen levels.

Existing models of liver -stage malaria that utilize primary human hepatocytes typically exhibit low in vitro infection efficiencies, possibly due to.

Strategies in Regenerative Medicine Matteo Santin Editor Strategies in Regenerative Medicine Integrating Biology with Materials Design 13 Editor Matteo Santin School of Pharmacy and Biomolecular Sciences University of Brighton [email protected] ISBN e-ISBN DOI / Library of Congress Control Number:.

Home; Executive Summary; VISION; VISTA. The Warburg apparatus is a manometric respirometer which was used for decades in biochemistry for measuring oxygen consumption of tissue homogenates or tissue slices. The Warburg apparatus has its name from the German biochemist Otto Heinrich Warburg () who was awarded the Nobel Prize in physiology or medicine in for his “discovery of the .